Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 170 |
Cambridge, Massachusetts
Overview: The Scientist, Process Sciences will be responsible for development, characterization and scale-up of speciality starting materials used in the Oligo DS manufacture processes. The successful candidate will work closely with intern...
2h
| Job Type | Full Time |
Sr. Manager, Global Demand Planning
Cambridge, Massachusetts
Overview: The Senior Manager, Global Planning is a key member of the Global Supply Planning Organization and is responsible for ensuring uninterrupted supply to all Alnylam patients both late-stage clinical and commercial, in line with corp...
2h
| Job Type | Full Time |
Senior Associate Scientist, Ligand Discovery
Cambridge, Massachusetts
Overview: The Delivery Sciences team at Alnylam is seeking a Senior Associate Scientist to contribute to our ligand discovery efforts for expanding RNAi delivery to all tissues. The successful candidate will help drive in vitro ligand selec...
2h
| Job Type | Full Time |
Associate Director, Quality Technology Delivery
Cambridge, Massachusetts
Overview Alnylam is seeking a results-oriented and execution-focused leader to serve as Associate Director, Quality Technology Delivery, responsible for delivering and supporting IT systems that enable Quality Management System (QMS) proces...
2h
| Job Type | Full Time |
Associate Director, Lab Computing and Facilities Technology
Cambridge, Massachusetts
Overview Alnylam is seeking an experienced and hands-on technology leader to serve as Associate Director, Lab Computing and Facilities Technology, a role focused on delivering reliable IT infrastructure, operational support, and compliance ...
2h
| Job Type | Full Time |
Associate Director, Laboratory Informatics Platforms
Cambridge, Massachusetts
Alnylam is seeking a strategic and delivery-oriented technology leader to serve as Associate Director, Laboratory Informatics Platforms. This role is responsible for the delivery, evolution, and operational stewardship of core laboratory in...
2h
| Job Type | Full Time |
Director, Cyber Defense Principal Engineer
Cambridge, Massachusetts
Overview Alnylam is pioneering RNAi therapeutics and scaling rapidly across research, development, and global commercialization. The Director, Cyber Defense will play a critical role in designing and advancing our next-generation cyber defe...
2h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview Alnylam's Translational Research group is seeking a highly motivated Metabolomics Scientist to join our team. We use untargeted and targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based omics and computational bi...
15h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The VP, Head of Global Strategic Sourcing, will serve as a key enterprise leader responsible for setting and executing Alnylam's global strategic sourcing, supplier management, and third-party risk strategy. As a member of the Fin...
15h
| Job Type | Full Time |
Senior Medical Director, Clinical Research - Neurodegeneration
Cambridge, Massachusetts
Overview Alnylam Pharmaceuticals is seeking an imaginative physician drug developer. This is an opportunity to provide clinical leadership in developing RNAi therapeutics in Alnylam's rapidly expanding portfolio, which spans the areas of ra...
24h
| Job Type | Full Time |