New

Senior Director, AI and Analytics

Alnylam Pharmaceuticals
paid time off
United States, Massachusetts, Cambridge
675 West Kendall Street (Show on map)
Jan 20, 2026
Overview We are seeking a Senior Director, AI and Analytics with a passion for architecting solutions, building systems, and delivering real business impact through hands-on contribution. As Senior Director, you will own the enterprise AI capability, leading a small, high-caliber team while staying actively engaged in solving our most complex technical challenges. This role blends strategic leadership with meaningful hands-on work, with approximately 10-20% of your time dedicated to building, reviewing, and advancing production-grade AI/ML systems.This is a role for a deeply technical leader who enjoys staying close to the work. You'll thrive here if you're excited to design and deploy modern ML solutions, collaborate closely with engineers, and regularly engage with Python and frameworks like PyTorch as part of your day-to-day leadership. What You'll Do AI Strategy & Technical Leadership Define and execute enterprise AI strategy across R&D, clinical, manufacturing, and commercial Architect end-to-end AI/ML solutions from ideation through production Establish technical standards and governance for regulated environments Lead evaluation of emerging AI technologies (LLMs, generative AI, foundation models) Hands-On Engineering Architect and implement production ML systems using modernMLOpspractices Write production Python code for ML pipelines, model training, and inference Build/deploy models usingPyTorch, TensorFlow, scikit-learn on AWS SageMaker or Databricks ML Own theMLOpsstack and tackle complex technical challenges directly Team Leadership Build and mentor 1-3 highly skilled AI engineers Foster experimentation, scientific rigor, and continuous learning Recruit world-class talent; lead from the front on hardest problems Business Partnership Partner with R&D, Clinical Ops, Manufacturing, and Commercial to translate challenges into AI solutions Communicate AI concepts and trade-offs to executive stakeholders Drive adoption and measurable ROI across the organization AI Education & Community Lead AI education initiatives across the organization-democratizing AI knowledge at all levels Regularly explore and demo new AI capabilities and technologies to keep the broader community engaged and skills sharp Foster a culture of AI literacy and experimentation enterprise-wide Strategic Vendor Partnerships Build andmaintaindirect relationships with key AI platform partners including Google, Anthropic, Microsoft, and other leading vendors Leverage vendor partnerships forearly accessto capabilities, technical support, and strategic roadmap alignment Serve as primary technical liaison for AI vendor engagements and evaluations Requirements 10+ years building production AI/ML systems; 5+ years in leadership Deep ML expertise: supervised/unsupervised learning, deep learning, NLP, computer vision, time series, causal inference Expert Python withPyTorch, TensorFlow, scikit-learn,XGBoost MLOpsexperience:MLflow, Kubeflow, SageMaker, Databricks ML Strong software engineering: Git, CI/CD, Docker/Kubernetes, API development LLM/generative AI experience (GPT, Claude, Llama) Modern data platforms: Snowflake, Databricks, Airflow,dbt, Spark AWSexpertisepreferred Business & Leadership (Required) 5+ years in biotech, pharma, or data-intensive industry applying AI at scale AI domain knowledge in at least one area: drug discovery, clinical trials, manufacturing optimization, or commercial analytics Experience in regulated environments 5+ years leading AI/ML teams with hands-on technical mentorship Track recordtranslating business problems into ML solutions with measurable impact Matrix organization experience; comfortable with influence over authority #LI-LN1 U.S. Pay Range $233,800.00 - $316,300.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers AboutAlnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer. >