Clinical Research Coordinator

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

Additional Job Details (if applicable)

The Brain Modulation Lab (Department of Neurosurgery, Massachusetts General Hospital) is a human systems neuroscience lab that studies brain

electrophysiology and behavior in patients undergoing surgery for epilepsy,

movement disorders, and psychiatric disease. The goal of our work is to facilitate the development and optimization of electrical and biological brain modulation therapies by addressing critical gaps in our understanding of human brainfunction.

We are looking for a motivated, detail-oriented, and talented individual to

coordinate a clinical research study of deep brain stimulation (DBS) for

Parkinson's disease and to assist in the acquisition and management of neural

and behavioral data. The study focuses on Evoked Resonant Neural Activity

(ERNA), a brain signal elicited by electrical stimulation and recorded directly

from the DBS electrode. We record ERNA during DBS implantation surgery and

measure patients' motor responses to stimulation at postoperative programming visits. The long-term goal is to make DBS surgery and programming faster and more widely available. The Clinical Research Coordinator will work under the supervision of the PIs (Alan Bush, PhD, and Mark Richardson, MD, PhD), in close collaboration with Todd Herrington, MD, PhD (Director of the MGH Deep Brain Stimulation Program), Pranav Nanda, MD, MPhil (Co-Director, Brain Modulation Lab) and other research scientists, and will routinely interact with patients.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

* Screen and recruit patients with Parkinson's disease who are scheduled

for DBS surgery, working with the neurosurgery and neurology clinical

teams, and assist with the informed consent process.

* Coordinate research activities around clinical care, including surgery

dates, postoperative imaging, and programming visits.

* Assist with experiment set-up, execution, take-down, and data collection

in the operating room during DBS electrode implantation surgery, in

both awake and asleep (general anesthesia) procedures. This include

preparing research, recording equipment, and cables, and coordinating

with the surgical, anesthesia, and nursing teams.

* Set up and run quantitative motor assessments during postoperative

DBS programming visits, following study procedures. These include

video recordings, wearable sensors (surface EMG and accelerometers),

and audio.

* Administer cognitive and behavioral tasks to inpatients undergoing

intracranial monitoring for epilepsy treatment. Task administration on

weekends may be required, but will be done on a rotating schedule.

* Access patient charts to derive data related to DBS surgery and

programming, collect patient outcome measures following surgery, and

develop and perform procedures for tracking surgical outcomes.

* Consolidate, de-identify, and manage intracranial, imaging, video, and

wearable-sensor data using Excel, MATLAB, Python, and standard

neurological data processing software. Improve, debug, and modify pre-

processing pipelines.

* Document and maintain specific protocol information and

communications according to established guidelines.

* Document research activities and maintain research databases (e.g.,

REDCap).

* Maintain confidential patient files, including all correspondence,

protected health information (PHI), raw data, and follow-up status of

research study participants.

* Assist with drafting essential study documents and preparing materials

for IRB submissions.

* Attend and prepare summaries of relevant clinical planning and lab

meetings.

* Purchase equipment and supplies and maintain communications with suppliers.

Pay Range

Grade