Postdoctoral Research Associate - Human Organoid/Assembloid Models of Schizophrenia-associated Risks
 Society for Neuroscience | |
 United States, Tennessee, Memphis | |
 Sep 11, 2025 | |
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Postdoctoral Research Associate - Human Organoid/Assembloid Models of Schizophrenia-associated Risks
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Job Details Job Description
A postdoctoral position is available for a highly motivated individual interested in the neural circuit mechanisms of schizophrenia. Our laboratory conducts 2-photon laser-scanning microscopy imaging and electrophysiologic recordings of neuronal activity in human induced pluripotent stem cell (hiPSC)-derived organoids and assembloid models, with a focus on 22q11 and 3q29 deletion syndromes. These syndromes are associated with a high risk of psychiatric disorders, especially schizophrenia. Preference will be given to applicants who have obtained a PhD in developmental neuroscience, cell biology, or related fields within the last 3 years and who have experience in organoid development, patch-clamp techniques, 2-photon imaging, and computational neuroscience. The successful candidate will lead an independent research project dedicated to identifying abnormal synaptic and neuronal activities in circuits of human models of 22q11.2 and 3q29 deletion syndromes, two rare conditions that confer the highest genetic risks of schizophrenia. Qualifications
Research Environment The laboratory is equipped with two 2-photon microscopes and multiple tools for performing single-cell electrophysiologic experiments in brain slices or human organoids. The successful candidate will join a diverse team of researchers whose efforts are directed toward understanding behavior at the levels of neural circuits, individual neurons, synapses, and molecules. The laboratory is part of the Department of Developmental Neurobiology, which houses specialized departmental shared resources, including the following:
In addition, numerous institutional shared resources and core facilities provide access to advanced technologies and expertise. Compensation & Application St. Jude Children's Research Hospital offers an excellent salary and benefits package and is an equal opportunity employer. Interested applicants should send their CV and the names and contact information of 3 references to: Stanislav Zakharenko, MD, PhD St. Jude Children's Research Hospital stanislav.zakharenko@stjude.org St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude. Company At St. Jude Children's Research Hospital, we know what can be achieved when the brightest minds meet new opportunities. That's why we provide world-class facilities, state-of-the-art technologies, and extraordinary support to advance treatments and cures. The result is a collaborative environment where everyone receives the resources, support and encouragement to grow and be the force behind the cures. Company info
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