Technical Project Manager, Therapeutic Discovery Domain

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Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche's Research and Early Development organizations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new computational sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.

Within the CoE organization, the Data and Digital Catalyst organization drives the modernization of our computational and data ecosystems and integration of digital technologies across Research and Early Development to enable our stakeholders, power data-driven science and accelerate decision-making.

The Opportunity

We are seeking a Technical Project Manager (TPM) to partner with the Therapeutics Discovery Domain Head and a small team to drive progress in our Therapeutics Discovery portfolio of initiatives. The Data and Digital Catalyst Domains are accountable for stakeholder partnership to define our "why", prioritize our "what" and drive product family strategy & leadership to realize our collective impact and outcomes. More specifically, the Therapeutics Discovery Domain provides solutions that enable therapeutic molecule design, synthesis, testing, and learning from results. In this role, you will bring expertise and experience from project, program, portfolio, and change management capabilities. With these capabilities, you will guide and support the Domain Head and Product Family Leads to drive clear outcomes in our portfolio and serve as a key enabler and integrator-bringing clarity, structure, and momentum to technically complex and organizationally nuanced efforts. This is a unique opportunity to work at the critical intersection of state of the art biology, medicinal chemistry, automation, informatics, and AI/ML -- bringing all these together to accelerate discovering life-changing therapeutics. You will work with world class experts in multiple drug discovery modalities and machine learning and artificial intelligence.

You will make pivotal contributions to the future of the Data and Digital Catalysts, CoE, and Research and Early Development by:

• Guiding teams to apply fit-for-purpose project and program management approaches tailored to the complexity of each initiative in close collaboration with product family leads and Domain Head

• Consistently drive toward Domain goals while balancing ambiguity, shifting priorities, and cross-functional complexity within the Technical Innovation Domain and across DDC Domains

• Developing and maintaining cross-product family roadmaps in alignment with Domain priorities and its north star

• Proactively identifying risks and integration points and managing interdependencies across product families and technical platforms and initiatives to ensure continuity of execution

• Serving as a trusted thought partner to the Domain Head to manage a vast network of scientific and technical stakeholders across functions and geographies

• Facilitating alignment and buy-in for multiple stakeholder groups within gRED and across pRED

• Tracking key milestones, dependencies, and resources across product families and coordinating holistically across all Domains in DDC

• Communicating progress and risks to the Domain team and transparently to leadership and stakeholders as needed

• Enabling the Domain Team to deliver meaningful outcomes and accelerate impact in a R&D setting

• Leading by example to establish and demonstrate the culture and working environment of this new organization aligned with our values.

Who you are

• Bachelors Degree in a scientific or technical field; MBA or PhD is an advantage

• 7+ years of experience with informatics initiatives in Pharma, with R&D process understanding; specifically in the pre-clinical drug discovery setting

• Demonstrated success managing complex informatics or software development projects within scientific or technical domains

• High level of business savvy, flexibility and ability to understand rapidly shifting stakeholder and technical landscape

• Strong systems thinking and the ability to connect technical solutions in a holistic view

• Pragmatic and adaptable, able to lead through ambiguity and influence without authority

• Demonstrates high emotional intelligence and inclusive collaboration skills

• Recognized for bringing structure and momentum to complex, cross-functional initiatives

• Operates with transparency, curiosity, and a continuous improvement mindset

• Experience in stakeholder management, change enablement, and fostering cross-functional collaboration

• Familiarity with scientific data lifecycles, FAIR data principles, and modern informatics platforms

• Proficiency in tools such as Smartsheet, JIRA, Confluence, and Google Suite

• Comfort engaging with both technical and scientific content and stakeholders

• Thrives in ambiguity, identifying opportunities, fostering a growth mindset, and effectively communicating and influencing in complex environments

The expected salary range for this position based on the primary location of California is $142,200-$264,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

#ComputationCoE

Relocation benefits are available for this posting.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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