This position is only for a 6-month appointment. The Research Assistant will join the research laboratory of Dr. Yuriy M. Usachev to perform foundational research on the mechanisms of neuronal signaling and circuitry, pain transmission and epilepsy. The Usachev lab focuses on the role of mitochondria in the regulation of synaptic activity, seizures, epilepsy and neurotoxicity. An additional line of projects examines the role and mechanisms of neuro-immune interaction in the periphery and in the central nervous system in controlling nociceptive processing and chronic pain. Multiple state-of-the art techniques are established in the lab, including multiphoton in vivo microscopy, EEG/EMG recording, Ca2+ imaging in cell culture, spinal cord and brain slices, patch-clamp recordings, opto- and chemo-genetic approaches and large array of mouse behavioral testing. Position Responsibilities * Perform molecular and cell biological studies with minimal oversight. This includes but is not limited to electrophysiological patch-clamp recordings, fluorescent imaging in intact spinal cord and/or brain slices, in vivo electrophysiology and imaging, and physiological experiments in mice. Training will be provided. * Carry out data analysis for electrophysiological and imaging experiments, which involves programming using JavaScript, Python, React, GraphQL, SQL and other packages. * Assist in the maintenance of lab equipment, monitoring lab inventory, arranging service contracts, and interfacing with technicians and vendors * Assist graduate students and postdocs with experiments. Education Requirements * Requires a bachelor's degree in a biomedical related field, other related science program, or equivalent combination of education and progressively responsible experience in a research laboratory environment. Experience Requirements * Previous research experience using patch-clamp electrophysiology and live imaging in a laboratory. * Excellent written and verbal communication skills, organizational skills, and interpersonal skills. * Experience with data analysis and programming. * Ability to work independently while being accountable and efficient with time management. Desired Qualifications * Experience with patch-clamp electrophysiology. * Experience with in vitro/ex-vivo and in vivo live imaging. * Experience with data analysis and programming. * Familiarity with surgical mouse procedures such as stereotaxic injections.
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University of Iowa
Jul 25, 2025