Biosensor Core Research Associate I - 135059

The UCSD Department of Pharmacology is one of two basic science units in the School of Medicine where world-class researchers investigate the molecular basis of human diseases. The faculty are internationally renowned for their strength in elucidating basic cellular and molecular mechanisms of signal transduction that lead to innovative drug target identification and ultimately to drug discovery. The faculty also play a major role in medical and graduate student training, providing educational and programmatic offerings that span several disciplines, and provide diversity to meet the interests of a broad spectrum of students and scholars. More than one hundred trainees at the graduate student and postdoctoral level, as well as a staff of more than 50 research technicians and department administrators interact closely with the faculty. The diverse mix of ages, backgrounds, and talents creates a robust work environment with challenging career opportunities and a commitment to continued growth potential. We constantly seek to recruit highly motivated, technologically-advanced and interested individuals to become a part of our dynamic exploratory research and educational environment.The UCSD Biosensor Core, housed within the Department of Pharmacology, is a first-of-its-kind facility dedicated exclusively to genetically encoded biosensors and optogenetic tools. By bridging the gap between novel molecular designs and end users, we make these advanced technologies more accessible, rigorous, and reproducible. From selecting the right probe to troubleshooting experimental designs, our mission is to help researchers illuminate dynamic biological processes with greater clarity and confidence. We provide training, consultation, and a shared repository of proven biosensors so that you can focus on discoveries rather than tool development.

Under supervision, incumbent will assist with standard experimental research techniques, cell culture, live cell imaging, and data analysis. Incumbent will perform laboratory maintenance duties including ordering supplies, making buffers, and handling reagent requests. Incumbent will oversee undergraduate helpers in making buffers and learning other lab skills. Incumbent must interact easily with a diverse array of faculty, postdoctoral scholars, students, and research technicians who will be utilizing the Biosensor Core's services.

• Theoretical knowledge of chemistry, biochemistry or biology, or other related fields.

• Knowledge and experience in basic laboratory procedures and equipments, including sterile techniques, preparation of buffers and media, cell culture, PCR, plasmid preps, and protein analysis and purification.

• Manual dexterity to perform experiments and manipulate lab equipment.

• Ability to maintain careful, legible and well-organized laboratory notes.

• Ability to follow basic research protocols and to understand and execute both written and verbal instructions and tasks on schedule.

• Experience with performing protein assays and protein gel electrophoresis.

• Knowledge and understanding of laboratory safety and ability to work carefully with potentially harmful agents.

• Tact and diplomacy to interact with a variety of individuals including faculty, staff, students and foreign scholars.

• Willingness to learn new techniques.

• Attention to protocol and details.

• Ability to work well with others; take orders and explain protocols to others.

• Ability to work independently and cooperatively.

• Experience with and skill in using computers.

• Knowledge of microscopy techniques.

• Knowledge of protein purification techniques.

• Experience with genetically encoded biosensors.

• Experience with live-cell assays and fluorescence microscopy.

• Employment is subject to a criminal background check.

• Willingness to work evenings and weekends, if necessary.

• Willingness to work with hazardous materials.

If employed by the University of California, you will be required to comply with our Policy on Vaccination Programs, which may be amended or revised from time to time. Federal, state, or local public health directives may impose additional requirements.

If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.

UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!

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